Experience of using Immune Chromatography test for Diagnostics of Pneumococcal Pneumonia
Nikolenko, V.V.; Feldblyum, I.V.; Vorobieva, N.N.; Golodnova, S.O.; Semerikov, V.V.; Polushkina, A.V.; Pavroz, K.A.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 3: 18-24
2015
ISSN/ISBN: 0372-9311 PMID: 26259265 Document Number: 684689
Justification of the use of immune chromatographic analysis for diagnostic of pneumococcal pneumonia. Sensitivity and specificity of an immune chromatographic method (Binax Now test system) was studied for verification of pneumococcal pneumonia. Approbation of this method for etiologic deciphering of pneumonia in 260 patients hospitalized in infectious hospital was carried out. A high sensitivity (84.8%) and specificity (90.5%) of the chromatography test was established. Streptococcus pneumoniae antigen in urine of patients with community acquired pneumonia was determined 3.6 times more frequently when immune chromatographic test was used compared with bacteriological study of nasopharyngeal swab and 1.8 times more frequently compared with sputum bacteriological study. Application of immune chromatographic express test Binax Now could be recommended for timely verification of pneumococcal pneumonia along with bacteriological methods of study.