Diabetic kidney disease: current management and potential future options
Krzesinski, J.-M.; Scheen, A.J.
Revue Medicale Suisse 11(483): 1534-1538; 1540-1542
2015
ISSN/ISBN: 1660-9379 PMID: 26502579 Document Number: 684166
The diabetic kidney disease is the most frequent cause of end stage renal disease in Western countries. Its detection is obtained by simultaneously measuring urinary albumin excretion and estimating glomerular filtration rate through serum creatinine dosage. Many type 1 and type 2 diabetic patients can present decreased glomerular filtration rate before the occurrence of increased urinary albumin. While waiting for promising new pharmacological approaches currently evaluated in clinical trials, the best approach to stop the epidemic of diabetic nephropathy remains an early and individual multifactorial approach controlling the glucose level (without inducing hypoglycaemia), blood pressure (using a renin-angiotensin blocker), dyslipidaemia and over-weight.