Prospective Synthetic Matrices for the Reconstruction of Tracheal Defects in Cancer Patients
Kiselevsky, M.V.; Sitdikova, S.M.; Anisimova, N.Y.; Polotsky, B.E.; Davidov, M.I.
Voprosy Onkologii 61(3): 323-328
2015
ISSN/ISBN: 0507-3758 PMID: 26242141 Document Number: 684114
A replacement of major defects of the trachea remains a challenge despite numerous attempts to use for this purpose various options of autologous and allogeneic implants as well as synthetic matrixes. The most prospective direction is to create tracheal matrixes based on biocompatible porous or fibrous materials that mimic native tissues and provide the proliferation of multipotent cells. This review summarizes current data regarding the development of experimental research and clinical testing of biocompatible tracheal matrixes, which were created using innovative technologies.