MicroRNAs and prostate cancer
Xu, W.-t.; Jia, Y.-j.; Li, X.-j.; Chen, J.
Zhonghua Nan Ke Xue 21(5): 458-462
2015
ISSN/ISBN: 1009-3591 PMID: 26117946 Document Number: 684048
Prostate cancer (PCa) is one of the most common malignancies in the urinary system of males. A growing number of studies have shown that microRNAs, as small ribonucleic acid molecules and a class of non-coding small RNAs, are closely related with PCa and a variety of microRNAs are abnormally expressed in it. This article focuses on the roles of microRNAs in the occurrence and progression of PCa, with a description of differentially expressed microRNAs in PCa and an analysis of their association with its prognosis as well as their correlation with chemotherapy, androgen receptors, and metastasis of PCa.