Non-invasive brain stimulation for Parkinson's disease
Gajo, G.; Pollak, P.; Lüscher, C.; Benninger, D.
Revue Medicale Suisse 11(472): 983
2015
ISSN/ISBN: 1660-9379 PMID: 26062225 Document Number: 683584
Parkinson's disease (PD) is a major socio-economic burden increasing with the aging population. In advanced PD, the emergence of symptoms refractory to conventional therapy poses a therapeutic challenge. The success of deep brain stimulation (DBS) and advances in the understanding of the pathophysiology of PD have raised interest in non-invasive brain stimulation (NIBS) as an alternative therapeutic tool. NIBS could offer an alternative approach for patients at risk who are excluded from surgery and/or to treat refractory symptoms. The treatment of the freezing of gait, a major cause of disability and falls in PD patients, could be enhanced by transcranial direct current stimulation (tDCS). A therapeutic study is currently performed at the Department of Neurology at the CHUV.