Optimization of Surgical Strategy for the Treatment of Thyroid Nodules
Skorobogatov, V.M.; Makanin, M.A.; Gurdenidze, V.V.
Klinicheskaia Meditsina 93(2): 72-76
2015
ISSN/ISBN: 0023-2149 PMID: 26117923 Document Number: 682682
This retrospective analysis of the results of surgical treatment involved 1006 patients with thyroid nodules operated at P V Mandryka Medical Educational and Scientific Centre in 1990-2007. Organ-preserving surgery was necessary to minimize the frequency ofpostoperative complications and maintain the hormone-producing thyroid function. The results of analysis of morphological structure of both nodular and surrounding healthy tissues were used to plan optimal extirpation of the thyroid nodule from the surrounding tissue. Circulatory disturbances with the appearance of fibrotic changes occurred in 69.7% of the cases; thyroiditis developed in 38.8% of the patients. Analysis of repeated operations showed that the risk of relapse depends on etiology and morphological structure ofthe nodule rather than the extent of surgical intervention. Organ-preserving surgery and consideration of endocrinologicalfactors ensured successful treatment of 89.3% of the patients.