Squamous cell carcinoma developing in necrobiosis lipoidica in a diabetic patient
Kolovics, J.; Mattes, L.P.; Andersen, K.E.; Beck-Nielsen, H.
Ugeskrift for Laeger 177(38): V01150054
2015
ISSN/ISBN: 1603-6824 PMID: 26376417 Document Number: 682361
The development of squamous cell carcinoma in chronic and/or non-healing ulcers associated with necrobiosis lipoidica (NL) is rare, but should be considered in diabetic patients. NL is a non-infectious granulomatous degenerative skin disease. The prevalence of NL in diabetic patients is estimated to 0,3-1,2%. Awareness of malignant transformation potential within a plaque of NL is crucial for early diagnosis and easy radical treatment. A case from our outpatient diabetes clinic is presented.