Loco-regional complications of pharyngitis: the example of Lemierre's syndrome
Tschopp, J.; Chuard, C.
Revue Medicale Suisse 11(489): 1844-1848
2015
ISSN/ISBN: 1660-9379 PMID: 26638515 Document Number: 682319
Pharyngitis is a common cause of consultation in ambulatory medicine. Although it is benign in most cases, serious complications may happen and must be recognized quickly. Lemierre's syndrome is one of them. It consists in the association of thrombosis of the internal jugular vein and septic emboli that generally involve the lungs and is classically associated with Fusobacterium necrophorum. It is usually found in young and healthy adults and has an estimated mortality of 5%. Diagnosis relies essentially on the characteristic presentation of the disease. Therapy consists of surgical drainage of purulent collections and necrotic tissues associated with a prolonged course of antibiotics. Some authors also recommend a anticoagulation.