Unusual lung finding of massive alveolar filling with foamy macrophages in congenital epidermolysis bullosa after amnion fluid aspiration in 15-day-old newborn without any clinical signs of respiratory impairment

Farkaš, D.; Švajdler Ml, M.án.; Fröhlichová, L.; Šprláková, J.; Iannaccone, S.F.šo.á; Szép, Z.án.; Nyitrayová, O.ľg.

Ceskoslovenska Patologie 51(2): 89-93

2015


ISSN/ISBN: 1210-7875
PMID: 25970721
Document Number: 682195
Epidermolysis bullosa represents a group of mechanobullous diseases which are most commonly genetically determined. We describe the case of a 15-day-old female newborn with congenital epidermolysis bullosa which was inflicted on aproximately 1/3 of her skin surface, who died because of incorrigible sepsis with multiorgan failure. The main topic of our report is a description of an unusual pulmonary finding of massive alveolar filling with foamy macrophages after amnion fluid aspiration, which contained a excessive amount of desquamated epidermal cells. Introduced case shows outstanding discrepancy of negative clinical finding on one side and massive histopathological finding on the other.

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