Insulin-Like Growth Factor-i is a Marker for the Nutritional State
Hawkes, C.P.; Grimberg, A.
Pediatric Endocrinology Reviews Per 13(2): 499-511
2015
ISSN/ISBN: 1565-4753 PMID: 26841638 Document Number: 682043
Measurement of the serum concentration of insulin-like growth factor-I (IGF-l) is generally used as a screening investigation for disorders of the growth hormone (GH)/IGF-I axis in children and adolescents with short stature. IGF-I concentration is sensitive to short-term and chronic alterations in the nutritional state, and the interpretation of IGF-I measurements requires knowledge of the child's nutritional status. In this review, we summarize the effects of nutrition on the GH/IGF-I axis, and review the clinical implications of these interactions throughout childhood, both in under-nutrition and over-nutrition.
Document emailed within 1 workday
Related Documents
Andresen, J.L.; Ehlers, N. 1998: Chemotaxis of human keratocytes is increased by platelet-derived growth factor-BB, epidermal growth factor, transforming growth factor-alpha, acidic fibroblast growth factor, insulin-like growth factor-I, and transforming growth factor-beta Current Eye Research 17(1): 79-87Wieczorek-Baranowska, A.; Nowak, A.; Michalak, E.; Karolkiewicz, J.; Pospieszna, B.; Rutkowski, R.; Laurentowska, M.; Pilaczyńska-Szcześniak, L. 2011: Effect of aerobic exercise on insulin, insulin-like growth factor-1 and insulin-like growth factor binding protein-3 in overweight and obese postmenopausal women Journal of Sports Medicine and Physical Fitness 51(3): 525-532
Milewicz, T.; Krzysiek, J.óz.; Sztefko, K.; Radowicki, S.ła.; Krzyczkowska-Sendrakowska, M. 2005: 17beta-estradiol regulation of human growth hormone (hGH), insulin-like growth factor-i (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) axis in hypoestrogenic, hypergonadotropic women Endokrynologia Polska 56(6): 876-882
Jaruratanasirikul, S.; Leethanaporn, K.; Pradutkanchana, S.; Sriplung, H. 1999: Serum insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) in healthy Thai children and adolescents: relation to age, sex, and stage of puberty Journal of the Medical Association of Thailand 82(3): 275-283
Jaruratanasirikul, S.; Leethanaporn, K.; Sriplung, H. 2000: The usefulness of serum insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) for evaluation of children with short stature Journal of the Medical Association of Thailand 83(6): 619-626
Armstrong, J.D.; Stanko, R.L.; Cohick, W.S.; Simpson, R.B.; Harvey, R.W.; Huff, B.G.; Clemmons, D.R.; Whitacre, M.D.; Campbell, R.M.; Heimer, E.P. 1992: Endocrine events prior to puberty in heifers: role of somatotropin, insulin-like growth factor-I and insulin-like growth factor binding proteins Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society 43(4 Suppl. 1): 179-193
Kolev, N.; Ivanov, S.; Kovachev, E.; Slavchev, S. 2014: The insulin-like growth factor IGFBP-1--specific marker for preterm delivery in pregnant women with clinical symptoms Akusherstvo i Ginekologiia 53(1): 6-8
Jaruratanasirikul, S.; Sriplung, H.; Leethanaporn, K. 1999: Serum insulin-like growth factor-1 (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) in healthy Thai children and adolescents: relation to height, weight, and body mass index Journal of the Medical Association of Thailand 82(10): 984-990
Velleman, S.G.; McFarland, D.C. 1999: Influence of fibroblast growth factor, insulin-like growth factor I, and transforming growth factor beta on satellite cell type i collagen expression and localization during differentiation Cytobios 100(394): 101-110
Kagan, A.; Altman, Y.; Zadik, Z.; Bar-Khayim, Y. 1997: Extracorporeal losses of insulin-like growth factor-i and insulin-like growth factor binding protein-3 in adult patients on CAPD Advances in Peritoneal Dialysis. Conference on Peritoneal Dialysis 13: 47-52
Tovar, A.R.; Halhali, A.; Torres, N. 1999: Effect of nutritional rehabilitation of undernourished rats on serum insulin-like growth factor (IGF)-i and IGF-binding proteins Revista de Investigacion Clinica; Organo del Hospital de Enfermedades de la Nutricion 51(2): 99-106
Deinhofer, M.; Majemnik, C. 1996: Insulin-like growth factor i and insulin-like growth factor binding protein 3 in a steer with growth retardation Deutsche Tierärztliche Wochenschrift 103(4): 130-131
Ashton, W.S.; Degnan, B.M.; Daniel, A.; Francis, G.L. 1995: Testosterone increases insulin-like growth factor-1 and insulin-like growth factor-binding protein Annals of Clinical and Laboratory Science 25(5): 381-388
Kato, M. 1998: Biological and clinical analyses of the mechanism of growth retardation and the effect of recombinant human insulin-like growth factor-1 (rhIGF-1) treatment on glucose metabolism and growth in leprechaunism with severe insulin resistant diabetes Hokkaido Journal of Medical Science 73(6): 613-625
Trippel, S.B.; Wroblewski, J.; Makower, A.M.; Whelan, M.C.; Schoenfeld, D.; Doctrow, S.R. 1993: Regulation of growth-plate chondrocytes by insulin-like growth-factor I and basic fibroblast growth factor Journal of Bone and Joint Surgery. American Volume 75(2): 177-189
Rickenlund, A.; Thorén, M.; Nybacka, A.; Frystyk, J.; Hirschberg, A.L.én. 2010: Effects of oral contraceptives on diurnal profiles of insulin, insulin-like growth factor binding protein-1, growth hormone and cortisol in endurance athletes with menstrual disturbance Human Reproduction 25(1): 85-93
Zhou, J.; Shi, Y.; Dong, M. 1999: The effect of insulin-like growth factor i and insulin on intrauterine fetal growth retardation Zhonghua Fu Chan Ke Za Zhi 34(4): 222-224
Su, Q.; Liu, Y. 1995: Expression of c-myc, c-erbB-2, insulin-like growth factor Ii andepidermal growth factor receptor in hepatitis B, cirrhosis and hepatocellular carcinoma Zhonghua Yi Xue Za Zhi 75(3): 144-146; 189
Yu, X.; Zhang, X.; Zeng, B. 2006: Expression of transforming growth factor beta1 and insulin-like growth factor i in the regenerated bones after low frequency micro movement Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 20(7): 685-689
Li, R.K.; Li, G.; Mickle, D.A.; Weisel, R.D.; Merante, F.; Luss, H.; Rao, V.; Christakis, G.T.; Williams, W.G. 1997: Overexpression of transforming growth factor-beta1 and insulin-like growth factor-I in patients with idiopathic hypertrophic cardiomyopathy Circulation 96(3): 874-881