Association between iron deficiency anemia and Helicobacter pylori infection among children under six years in Iran
Darvishi, M.; Ziari, K.; Mohebbi, H.; Alizadeh, K.
Acta Medica Iranica 53(4): 220-224
2015
ISSN/ISBN: 0044-6025 PMID: 25871019 Document Number: 681429
This study was conducted to evaluate the association between H. pylori infection and Iron deficiency anemia (IDA) among preschool children (age range: 40-75 months) at a tertiary referral hospital in Tehran.In a case-control study, the prevalence of H. pylori seropositivity was compared between 64 children with IDA diagnosis and 70 healthy non-anemic sex- and age-matched controls. Totally, 52 (81.3%) children with IDA and 10 (14.3%) non-anemic controls had a positive antibody level for H. pylori specific IgG and the difference between two groups was statistically significant (P<0.0001). H. pylori infection had a significant high prevalence among preschool patients with IDA. Eradication of H. pylori infection is recommended for patients with refractory IDA.