The use of Volatile Agents for Sedation in Children in the Intensive Care Unit
Babaev, B.D.; Ostreikov, I.F.; Shtatnov, M.K.; Apostolidi, E.Y.; Nikitin, V.V.; Nadbitova, R.A.
Anesteziologiia i Reanimatologiia 60(3): 19-22
2015
ISSN/ISBN: 0201-7563 PMID: 26415290 Document Number: 681068
Sedation is a controllable level of medication depression of consciousness during which protective reflexes, adequate breathing, and responsiveness to physical stimuli and verbal commands are retained A number of physical and psychological factors affect the psyche of patients in the intensive care unit. Central nervous system (CNS) is a primary target of action of anesthetics and analgesics, and the bi-spectral index reflects the level of sedation of CNS, regardless of what drug caused sedation. The aim of this study was to use volatile anesthetics sevoflurane and isoflurane in children for sedation in the intensive care unit. Constant use of the inhalation route of administration helps to maintain the desired level of sedation depth for the required period of time in patients who are on long-term sedation and is practical for correction.