Treatment of Extremely Premature Newborn Infant with Ino. Clinical Case
Radulova, P.; Slancheva, B.; Marinov, R.
Akusherstvo i Ginekologiia 54(9): 52-57
2015
ISSN/ISBN: 0324-0959 PMID: 26863798 Document Number: 680390
Prolonged inhaled nitric oxide (iNO) from birth in preterm neonates with BPD improves endogenous surfactant function as well as lung growth, angiogenesis, and alveologenesis. As a result there is a reduction in the frequency of the "new" form of BPD in neonates under 28 weeks of gestation and birth weight under 1000 gr. Delivery of inhaled nitric oxide is a new method of prevention of chronic lung disease. According to a large number of randomized trials iNO in premature neonates reduces pulmonary morbidity and leads to a reduction of the mortality in this population of patients. This new therapy does not have serious side effects. We represent a clinical case of extremely premature newborn infant with BPD treated with iNO.