Research Progress of Feasibility of Dendritic Cell Antifungal Vaccines
Fan, G.; Wang, L.; Wang, Y.; Zhao, P.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 32(3): 684-687
2015
ISSN/ISBN: 1001-5515 PMID: 26486000 Document Number: 679919
Fungal infection is an important clinical problem for patients with immune deficiency or immunosuppression. With deadly fungus infection case increasing, the development of antifungal vaccine attracts the attention of researchers. Dendritic cell (DC) is the unique antigen presenting cell (APC) to trigger the antifungal immune reaction, and recent studies indicate that the targeted vaccination strategy based on DC have prospective antifungal potentials. In this paper, we review the antifungal immunity mechanism and recent development of the targeted DC antifungal strategy.