Targeting Neuroinflammation for Treatment of Ischemic Stroke
Kokaia, Z.
Georgian Medical News 243: 84-87
2015
ISSN/ISBN: 1512-0112 PMID: 26087739 Document Number: 679612
Ischemic stroke is a major cause of adult disability. Stroke-induced brain damage is accompanied by inflammation - activation of resident microglia and infiltration of blood-circulating monocytes. The effect of these cells on neuro-plasticity and recovery after stroke could be detrimental as well as beneficial. The future challenge is to understand the mechanisms of action of immune cells on cellular plasticity occurring in post-stroke brain and divert them towards support of functional recovery.
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