Extractable/leachable substances from plastic materials used as pharmaceutical product containers/devices
Jenke, D.
PDA Journal of Pharmaceutical Science and Technology 56(6): 332-371
2002
ISSN/ISBN: 1079-7440 PMID: 12497770 Document Number: 6786
A review is provided related to the accumulation of organic and inorganic leachable substances from DEHP-plasticized PVC, polyolefin and various other related pharmaceutical plastic packaging materials. The review considers both the identification of such leachables as well as their reported levels in actual and simulated pharmaceutical products.
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