Psoriasis syndrome with its comorbidities
Piérard-Franchimont, C.; Piérard, G.E.; Delvenne, P.; Hermanns-Lê, T.
Revue Medicale de Liege 69(10): 555-558
2014
ISSN/ISBN: 0370-629X PMID: 25796750 Document Number: 678013
The recognition of a complex disorder associating skin psoriasis and its comorbidities has considerably progressed over recent years. Beyond the skin lesions, psoriatic arthritis, the metabolic syndrome, type II diabetes, cardiovascular disease, inflammatory bowel diseases, and some cancers represent a group of chronic systemic disorders. The process is initiated and sustained by an immunological pathway involving Th1, Th17 and Th22 lymphocytes. The recognition of this complex disorder indicates that the clinical impact of psoriasis is not exclusively limited to the skin only.