Asymptomatic cerebral infarctions: risk factors and cognitive impairment
Zhetishev, R.R.; Mikhaĭlova, N.A.; Ivashchenko2, R.A.; Kamchatnov, P.R.
Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova 114(3 Part 2): 3-6
2014
ISSN/ISBN: 1997-7298 PMID: 24781234 Document Number: 677908
Objectives. To study the risk factors of asymptomatic cerebral infarctions (AI) and their effect on cognitive functions. Material and methods. We examined 114 patients, aged from 53 to 88 years, including 58 patients with AI (group 1), 32 women and 26 men (mean age 66.5±7.3 yeas), and 56 patients with chronic cerebral ischemia (CCI) without a history of stroke and transitory ischemic attacks, (group 2), 36 women and 20 men (mean age 64.2±6.6 yeas). Results. Cardiovascular risk factors (arterial hypertension, diabetes mellitus, ischemic heart disease, atrial fibrillation) were more frequent in group 1. The results of neuropsychological testing revealed worse cognitive performance in patients with AI. Conclusions. The results confirmed the negative effect of AI on cognitive functioning and higher risk of CCI progression.