The study of quality characteristics of the hydrogel ointments and films based on copolymers divinyl esters of diethylene glycol
Bakirova, R.E.; Tazhbaeva, E.M.; Muravleva, L.E.; Fazylov, S.D.; Akhmetova, S.B.
Georgian Medical News 237: 64-70
2014
ISSN/ISBN: 1512-0112 PMID: 25617104 Document Number: 674044
The possibility of using a hydrogel based on divinyl ether co- and terpolymer of diethylene glycol as the backbone polymer for incorporating water-soluble medicinal substances was examined. The character of the influence of emulsifiers, plasticizers, high-boiling liquids and bioactive substances is defined within the changes of physical-chemical properties of obtained hydrogels. The obtained polyelectrolyte hydrogels by their homogeneity, dehydration and rheological characteristics may be of concern in function of matrices to create external prolonged-action dosage forms.