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Autologous serum eye drops for severe dry eye syndrome in a patient with chronic graft-versus-host disease: a case report

Mixon, B.; Mixon, J.; Isbey, E.K.; Sprinkle, S.

International Journal of Pharmaceutical Compounding 18(5): 370-377

2014

ISSN/ISBN: 1092-4221
PMID: 25577885
Document Number: 673719
We present the case of a 49-year-old woman with severe dry eye syndrome caused by chronic graft-versus-host disease that developed after an allogeneic hematopoietic transplant to treat acute myelogenous leukemia. After the use of commercially manufactured products for the treatment of dry eye failed to relieve her photosensitivity, blurred. vision, and severe bilateral ocular pain, she benefitted significantly from therapy with compounded autologous serum eye drops. Comments from that patient are included in this report, as are a formulation for the preparation of autologous eye drops and suggestions for their safe and effective use.

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