Top Abstract Purchase Related
Home
>
Node
>
Subnode

Research progress of effects of strontium ranelate on osteoarthritis

Wang, Y.; Dai, M.; Tian, F.; Zhang, L.

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 28(12): 1479-1483

2014

ISSN/ISBN: 1002-1892
PMID: 25826890
Document Number: 673195
To review the research progress focused on the effects of strontium ranelate (SR) on osteoarthritis. The relevant literature about the effects and mechanism of SR intervening osteoarthritis in recent years was extensively reviewed and comprehensively analyzed. SR not only could improve the microenvironment of bone metabolism in articular cartilage with osteoarthritis, promote activity of osteoblasts, and inhibit activity of osteoclasts, but also could adjust the expression of key proteases which affect cartilage formation, and therefore it has a potential protective effect on subchondral bone during the progression of osteoarthritis cartilage. SR is expected to become a drug of osteoarthritis disease remission, but further studies are needed to clarify the mechanism of SR in osteoarthritis, and finally confirm the best application dosage of SR in osteoarthritis treatment.

Document emailed within 1 workday
Secure & encrypted payments

Bunyaratavej, N. 2011: The action of Strontium ranelate: myth or reality Journal of the Medical Association of Thailand 94(Suppl 5): S35-S37
Rodríguez, J.; Escudero, N.D.; Mandalunis, P.M. 2012: Effect of strontium ranelate on bone remodeling Acta Odontologica Latinoamericana: Aol 25(2): 208-213
Reginster, J-Y.; Deroisy, R.; Jupsin, I. 2003: Strontium ranelate: a new paradigm in the treatment of osteoporosis Drugs of Today 39(2): 89-101
He, D.; Yin, M.; Luo, Y.; Wei, Q. 2012: Research progress of protective effects of alendronate on articular cartilage in osteoarthritis Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 26(10): 1187-1190
Gao, W.-w.; Zhang, N.; Yu, S.-w. 2014: Research progress on antitumor effects and mechanisms of phellinus Zhongguo Zhong Yao Za Zhi 39(21): 4165-4168
Sauer, R. 1971: The place of strontium-87m in bone scanning. Comparative studies with strontium-85 Schweizerische Medizinische Wochenschrift 101(31): 1129-1137
Llobet, J.M.; Colomina, M.T.; Domingo, J.L.; Corbella, J. 1992: Lack of effectiveness of several chelators in removing internally deposited strontium from mice following repeated parenteral strontium administration Veterinary and Human Toxicology 34(1): 7-9
Chen, S.-z. 2016: Research progress in anticancer effects and molecular targets of honokiol in experimental therapy Yao Xue Xue Bao 51(2): 202-207
Maetzel, A. 2002: The challenges of estimating the national costs of osteoarthritis: are we making progress? Journal of Rheumatology 29(9): 1811-1813
Sassine, A.; Bernard, C. 1972: Comparative study of the effects of calcium and strontium ions on myocardial membrane permeabilities Journal de Physiologie 65(Suppl 3): 497a
Fassbender, H.G. 1991: Osteoarthritis in the light of current research findings Therapeutische Umschau. Revue Therapeutique 48(1): 7-12
Read, S. 1994: The Strategy for Research in Nursing in England: Initial impact In May 1993, the Department of Health published The Report of the Taskforce on the Strategy for Research in Nursing, Midwifery and Health Visiting ( 1 ). The Taskforce had been appointed to consider the scope and objectives of research in England and the interfaces with other areas of health services research. Susan Read reports on its progress Nurse researcher 1(3): 72-84
Read, S. 1994: The Strategy for Research in Nursing in England: Initial impact In May 1993, the Department of Health published The Report of the Taskforce on the Strategy for Research in Nursing, Midwifery and Health Visiting ( 1 ). The Taskforce had been appointed to consider the scope and objectives of research in England and the interfaces with other areas of health services research. Susan Read reports on its progress Nurse researcher 1(3): 72-84
Shildrick, J.P. 1977: S.T.R.I. contract research on turfgrasses: a summary of progress under the sub-contract with the Natural Environment Research Council, 1974-77 Journal of the Sports Turf Research Institute 53: 85-92
Queneau, P.; Lejeune, E.; Veysseyre, C.; Titoulet, M.; Vallat, M.P.; Carraz, M. 1978: Our experience with the determination of serum anti-alphastaphylolysins and antigammastaphylolysins during infectious osteoarthritis. a personal series of 53 staphylococcal osteoarthritis cases, 14 cases of osteoarthritis from various germs, 47 extra-articular staphylococcal infections and 500 control subjects Revue du Rhumatisme et des Maladies Osteo-Articulaires 45(5): 325-333
Villafañe, J.Hugo.; Valdes, K.; Pedersini, P.; Berjano, P. 2019: Osteoarthritis: a call for research on central pain mechanism and personalized prevention strategies Clinical Rheumatology 38(2): 583-584
Snelling, S. 2008: Osteoarthritis Research Society International--12th Annual Meeting. 6-9 December 2007, Fort Lauderdale, FL, USA IDrugs: the investigational drugs journal 11(2): 82-86
Fujinaga, H.; Koike, K. 2011: Progress and perspective in HBV research Nihon Rinsho. Japanese Journal of Clinical Medicine 69(Suppl 4): 339-343
Lorenc, R. 1972: Progress in calcitonin research Postepy Biochemii 18(3): 455-471
Yang, F.-p.; He, Y.; Wang, Z.; Wang, Y.; Jiang, X.-r.; Shen, J.-s. 2016: Research progress of antipsychotics Yao Xue Xue Bao 51(12): 1809-1821