The bacille Calmette-Guérin vaccine may reduce the general child morbidity
Nissen, T.Nørrelykke.; Thøstesen, L.Marianne.; Birk, N.Marie.; Pihl, G.; Kjærgaard, J.; Stensballe, L.Graff.
Ugeskrift for Laeger 176(9)
2014
ISSN/ISBN: 0041-5782 PMID: 25096560 Document Number: 672514
For almost 100 years the bacille Calmette-Guérin (BCG) vaccine has been the primary prophylaxis of tuberculosis (TB). Recent studies suggest that reintroduction of the vaccine might be beneficial from a general child health perspective. Studies from West-Africa report that BCG vaccination at birth reduces child mortality and morbidity. We recently started "The Calmette Study" in Denmark to conduct a randomised clinical trial and collect firm evidence of the suggested hypothesis, that BCG vaccination at birth has beneficial unspecific effect on child health also in a high-income TB low-incidence country.