Rare Association of Myeloid leukaemia of Down Syndrome with Granulocytic Sarcoma
Obaid, M.A.; Bourusly, M.; Ancliff, P.; Al Matter, E.
Gulf Journal of Oncology 1(16): 101-104
2014
ISSN/ISBN: 2078-2101 PMID: 25316400 Document Number: 672199
We report an 18-months old boy with trisomy 21 who initially presented with myelodysplastic syndrome MDS, and later transformed into acute megakaryoblastic leukaemia AML. At presentation he was found to have some unusual findings namely multiple soft tissue masses over scalp, left elbow and over the knee joints as well as hard mass felt in left hip. Biopsy of soft tissue of scalp revealed granulocytic sarcoma. Generally granulocytic sarcoma is seen with AML-M2 and its association with AML-M7, to our belief has rarely been reported previously.