Current concepts in pathogenesis of age-related macular degeneration
Kubicka-Trząska, A.; Karska-Basta, I.; Romanowska-Dixon, Bżena.
Klinika Oczna 116(4): 277-282
2014
ISSN/ISBN: 0023-2157 PMID: 25906640 Document Number: 672094
Age-related macular degeneration is the leading cause of central blindness in elderly population of the western world. The pathogenesis of this disease, likely multifactorial, is not well known, although a number of theories have been put forward, including oxidative stress, genetic interactions, hemodynamic imbalance, immune and inflammatory processes. The understanding of age-related macular degeneration pathogenesis will give rise to new approaches in prevention and treatment of the early and late stages of both atrophic and neovascular age-related macular degeneration.