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Morphometric parameters of the neurodegenerative process in Parkinson's disease and chronic cerebral ischemia

Bogdanov, R.R.; Manannikova, E.I.; Abrabenko, A.S.; Maratkanova, T.V.; Kotov, S.V.

Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova 113(10): 40-44

2013

ISSN/ISBN: 1997-7298
PMID: 24300804
Document Number: 671352
Authors have compared the results of MRI volumetric morphometry of brain hemispheres, substantia nigra and red nucleus in patients with different stages of Parkinson's disease (PD), patients with early and developed stages of cerebrovascular disease and healthy people. Already in the early stage of disease, the degree of cerebral hemisphere atrophy was more pronounced in patients with cerebrovascular disease compared to PD patients. At the same time, multidirectional changes in the size of the substantia nigra were noted. This finding may be relevant for the diagnosis of PD in the early stages.

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