Parameters of thyroid glands functional units in diffuse toxic and nodular euthyroid goiter in population of border areas of Azerbaijan and Georgia
Ganieva, G.M.; Shadlinskiĭ, V.B.; Gogiashvili, L.E.; Tsagareli, Z.G.
Georgian Medical News 218: 67-72
2013
ISSN/ISBN: 1512-0112 PMID: 23787511 Document Number: 670753
The purpose of the study--estimate of thyroid tissue quantitative alteration features in different types of goiter on the operative material with a data of morphometry (stereometry) data, histology and electron microscopy in the border (neighboring) regions of Georgia and the Azerbaijan. Cohort study group made up thyroid specimens from 187 patients with nodular euthyroid and diffuse toxic goiter operated in the clinics of Azerbaijan Medical University (Baku) and the National Institute of Endocrinology in Tbilisi for the period 2010 - 2012. Results of the follicules and capillaries morphometric study indicate common clinico-morphologic manifestations of thyroid disorders in the studied regions of Georgia and Azerbaijan, as well as to: 1) determinate capacity to the hyperplastic processes in the thyroid parenchyma under the nodular euthyroid goiter, 2) the disbalance between the clinical manifestation of the disease and its growth potential, which is important to define the "biological behavior" of thyroid nodules, including relapse.