An initial study on the feasibility of diagnosing myocardial ischemia with CT first-pass myocardial perfusion imaging at rest
Wang, Q.; Qin, J.; Gai, L.-y.; Wang, Z.-g.; Guan, Z.-w.; Sun, Z.-j.; Dong, W.; Yang, L.; Chen, Y.-d.
Zhonghua Xin Xue Guan Bing Za Zhi 41(3): 199-204
2013
ISSN/ISBN: 0253-3758 PMID: 23879943 Document Number: 668053
To assess the feasibility and accuracy of CT first-pass myocardial perfusion imaging (CT first-pass MPI) at rest for diagnosis of myocardial ischemia. Results of adenosine-induced myocardial perfusion scintigraphy (MPS) were used as gold standard. Twenty-two patients with suspected or diagnosed coronary artery disease (CAD) were included and CT coronary angiography (CTCA) and MPS were performed within 2 weeks. CT first-pass MPI detected myocardial ischemia results through analyzing the raw date of CTCA were compared with MPS results. The sensibility, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of CT first-pass MPI at rest for detecting myocardial ischemia were 92% (12/13), 78% (7/9), 86% (12/14), 88% (7/8) and 86% (19/22), respectively. CT first-pass MPI at rest could detect myocardial ischemia with an accuracy similar to that of MPS.