Component-resolved diagnosis is a new era in clinical allergology
Mokronosova, M.A.; Korovkina, E.S.
Terapevticheskii Arkhiv 85(10): 4-9
2013
ISSN/ISBN: 0040-3660 PMID: 24437212 Document Number: 667371
The paper describes the fundamentals and benefits of a new allergy diagnostic technique based on recent advances in molecular biology and biotechnology. Component-resolved diagnosis allows IgE antibodies against purified molecules (individual allergen components) to be revealed. Microanalysis is made using microarrays with applied molecules (allergen components) obtained in a recombinant fashion or extracted from natural raw materials. The authors present a current classification of animal and plant allergens and show the value of component-resolved diagnosis in clinical practice, by using specific clinical examples.