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Liver functional state after fractures of leg bones in mice

Ocheretina, R.I.; Stogov, M.V.

Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 99(12): 1389-1396

2013

ISSN/ISBN: 0869-8139
PMID: 25464769
Document Number: 666701
The content of glycogen and lipids in the liver, relative liver weight, the volume of hepatocytes and their nuclei, nucleocytoplasmic index, content binucleated hepatocytes, the chemical composition of the bones of the injured limb segment was studied after 3, 7, 28 days after the fracture of the leg bone after fracture leg bone with background carbon tetrachloride intoxication in mice CBA (n = 134). After the fracture revealed functional changes in the liver at all stages of the experiment. The decrease in the liver glycogen content and lipids in the bone of the injured limb segment--collagen and phosphate--was found after fracture leg bone of against the background liver failure. Found that during the recovery period after leg bone fracture liver condition affects mineral and organic composition of the bone injured limb segment.

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