Endoscopic endonasal detection of cerebrospinal fluid leakage with topical fluorescein
Sato, T.; Kishida, Y.; Watanabe, T.; Tani, A.; Tada, Y.; Tamura, T.; Ichikawa, M.; Sakuma, J.; Omori, K.; Saito, K.
No Shinkei Geka. Neurological Surgery 41(8): 693-696
2013
ISSN/ISBN: 0301-2603 PMID: 23907476 Document Number: 666619
We evaluated the effectiveness of intraoperative topical application of fluorescein to detect the leakage point of cerebrospinal fluid(CSF)rhinorrhea. Three patients with CSF rhinorrhea were treated with an endoscopic endonasal technique. Ten percent fluorescein was topically used for intraoperative localization of the leak site. A change of the fluorescein color from brown to green due to dilation of CSF were recognized as evidence of CSF rhinorrhea. We repeated the procedure to detect any small defects. All CSF rhinorrheas were successfully repaired by this endoscopic endonasal approach. Topical application of fluorescein is simple and sensitive for identifying intraoperative CSF rhinorrhea.