Talc-induced pulmonary granulomas in drug addicts
Latartseva, L.N.; Kryvenko, O.N.
Arkhiv Patologii 75(4): 24-27
2013
ISSN/ISBN: 0004-1955 PMID: 24313188 Document Number: 664821
Among the diseases accompanied by granuloma formation in the lung, there is so-called granulomatosis developing in injection drug users who have been long injecting suspensions of oral medications containing talc and other water insoluble fillers. 102 deaths of chronic intravenous drug users were examined; 12 of whom showed pulmonary talc-induced granulomatosis. Their morphology was studied using polarized light microscopy. The main mechanisms of thanatogenesis in lethal cases within the first hours after intravenous injection of talc-containing oral medication suspensions are explained.