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Leukemoid reaction, a rare manifestation of autoimmune hemolytic anemia in a case of small duct primary sclerosing cholangitis

Salagre, K.D.; Sahay, R.N.; Patil, A.; Pati, A.; Joshi, A.; Shukla, A.

Journal of the Association of Physicians of India 61(10): 760-762

2013

ISSN/ISBN: 0004-5772
PMID: 24772740
Document Number: 664308
A 48 year old lady presented with jaundice and exertional breathlesness. Her laboratory reports showed anaemia, reticulocytosis, leucocytosis, elevated Lactate Dehydrogenase (LDH), alkaline phosphatase levels, hyperbillirubinemia and positive direct Coomb's test. After ruling out all the other causes of autoimmunity and hemolytic anemia, she was diagnosed as leukemoid reaction due to autoimmune hemolytic anemia with primary sclerosing cholangitis. Patient showed immediate improvement after corticosteroids.

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