Effects of soy protein supplement on overweight and obese population: meta-analysis of randomized controlled trials
Wu, J.; Dong, J.; Jiang, X.; Qin, L.
Wei Sheng Yan Jiu 42(2): 185-189
2013
ISSN/ISBN: 1000-8020 PMID: 23654091 Document Number: 664244
To study the effects of soy protein supplement on overweight and obese population. Randomized controlled trials (RCT) published from January 1988 to May 2012 observing the effect of soy protein supplement on overweight and obese population were collected. Meta-analysis was applied to estimate the standardized mean difference (WMD) and 95% confidence interval (95% CI). Among 13 RCTs, the number of the studies observing change of body weight, body mass index (BMI), fat mass and waist circumference were 12, 7, 7 and 11, respectively. Compared with the control group, the combined WMD (95% CI) of soy protein supplemented was - 1.04 kg [( -1.97) - ( -0.11)], -0.19 kg/m2 [(-0.41) - (0.02)], -0.99 kg [(-1.73) - (-0.24)] and - 0.94 cm [(-1.66) - (-0.21)], respectively. However, the protective effect of soy protein was only observed among studies conducted in Western population, but not in Asian population. Soy protein supplementation significantly decreased body weight, fat mass and waist circumference in overweight and obese population.