Hypertensive pregnancy in diabetes--risk factors and influence on future life
Gordin, D.; Groop, P.-H.; Teramo, K.; Kaaja, R.
Duodecim; Laaketieteellinen Aikakauskirja 129(9): 932-938
2013
ISSN/ISBN: 0012-7183 PMID: 23786105 Document Number: 664070
Pre-eclampsia and gestational hypertension are potentially dangerous entities causing maternal and fetal morbidity and mortality. Interestingly, the risk factors for these two conditions differ and it is thought that they also differ in their pathophysiological background. Notably, women with diabetes have an increased risk for de novo hypertension during pregnancy compared to non-diabetic subjects. However, among diabetic patients poor glycaemic control has been shown to increase the risk for pre-eclampsia. Furthermore, women with a history of pre-eclampsia suffer more often from cardiovascular disease later in life. New data regarding long-term effects of hypertensive pregnancies on late diabetic complications have been published that may be of clinical relevance in the prevention of these complications.