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Features of anesthesia in rats at abdominal operations

Smirnova, A.V.; Lagutina, L.D.; Trubitsina, I.E.; Vasnev, O.S.; Ianova, O.B.

Eksperimental'naia i Klinicheskaia Gastroenterologiia 5: 62-65

2012

ISSN/ISBN: 1682-8658
PMID: 23402173
Document Number: 663692
Nowadays, in Russia, diethyl ether is the most popular narcosis for rodent and particular rats. We had tested the new methods based on Zoletil 100 + XylaVet (15 mg/kg and 15-10-5 mg/kg) respectively. 6 conventional female rats were treated with this narcosis. The rats, early have narcotized by diethyl ether were investigated as control group. All of 6 treated with new narcosis animals died in early post-operative time. Interestingly enough, that organ toxicity, except neurologic toxicity, was not described in literature and manuals. We assume that this new narcosis is the cause of portal thromboses.

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