Case for diagnosis. Atypical fibroxanthoma
Hammerschmidt, M.; Azevedo, L.Menezes.de.; Ruaro, A.; Werner, B.; Nascimento, A.do.; Amaral Filho, E.Augusto.
Anais Brasileiros de Dermatologia 87(4): 647-648
2012
ISSN/ISBN: 0365-0596 PMID: 22892788 Document Number: 663426
Atypical fibroxanthoma is a rare cutaneous tumor found mainly in elderly people on sun-exposed areas of the body. Histologically, atypical fibroxanthoma is considered a malignant fibrous histiocytoma with bizarre neoplastic cells, marked pleomorphism, hyperchromatic nuclei and abundant mitoses. It must be differentiated from other skin tumors, usually by immunohistochemistry, since its diagnosis is made by exclusion.