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Relationship gene polymorphism adipor1 with cardiovascular risk in patients with nonalcoholic fatty liver disease

Kolesnikova, O.

Georgian Medical News 213: 40-44

2012

ISSN/ISBN: 1512-0112
PMID: 23293232
Document Number: 663176
The aim of the research was to study the link between the polymorphic gene ADIPOR1 and the development of cardiovascular risk in patients with non-alcoholic fatty liver disease (NAFLD). It was found that the carriers of the G allele ADIPOR1 rs 1342387, compared with the carriers of the A allele have a potentially higher degree of cardiovascular risk. NAFLD carriers of the G genotype ADIPOR1 observed proatherogenic lipid profile and a significant increase in the thickness of the intima-media. The results confirm the modulation of genetic factors in the implementation of cardiovascular risk in patients with NAFLD.

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