Changes of oxidative homeostasis in acute experimental cholecystitis
Iakubovskiĭ, S.V.; Leonovich, S.I.; Kondratenko, G.G.; Popova, I.I.
Eksperimental'naia i Klinicheskaia Farmakologiia 75(12): 34-36
2012
ISSN/ISBN: 0869-2092 PMID: 23700667 Document Number: 662208
Variations of the indices of endogenous intoxication, lipid peroxidation, oxidative modification of proteins, and antioxidant system operation have been studied in animals with acute experimental cholecystitis. The possibility and effectiveness of using succinate-containing drugs reamberin and mexidol for the correction of these impairments has been assessed. In the present study, reamberin effectively reduced the intensity of lipid peroxidation and protein modification in experimental animals.