Oral fluid nanosensor test: saliva as a diagnostic tool for oral health
Pujari, M.; Bahirwani, S.; Balaji, P.; Kaul, R.; Shah, B.; Daryani, D.; Iqbal, S.
Journal of the California Dental Association 40(9): 733-736
2012
ISSN/ISBN: 1043-2256 PMID: 23097828 Document Number: 662191
High-impact diseases, especially cancer, are challenging to diagnose without supplementing laboratory testing. Even with laboratory tools, definitive diagnosis often remains elusive. The oral fluid nanosensor test technology platform combines cutting-edge technologies--such as self-assembled monolayers, bionanotechnology, cyclic enzymatic amplification, and microfluidics--with several well-established techniques including microinjection molding, hybridization-based detection, and molecular purification. The intended use of the OFNASET is for the point-of-care multiplex detection of salivary biomarkers for oral cancer.