Febrile pancytopenia and hepatosplenomegaly as leading symptoms of visceral leishmaniasis
Polák, P.; Svoboda, R.; Kubáčková, P.; Brychtová, Y.; Panovská, A.; Nohýnková, E.; Husa, P.; Freibergerová, M.; Pařízková, R.; Snelerová, M.; Pýchová, M.; Kamelander, J.
Vnitrni Lekarstvi 58(10): 761-764
2012
ISSN/ISBN: 0042-773X PMID: 23121063 Document Number: 661784
The authors present a case report of a patient with febrile pancytopenia, hepatosplenomegaly and weight loss as main symptoms of visceral leishmaniasis. Standard treatment regimen with amphothericin B led to relapse of the disease after several weeks. The definitive cure of the disease was achieved with cytostatic miltefosin (Impavido©), which is not registered in the Czech Republic. The aim of this article is to point out this imported protozoan infection and its basic clinical and laboratory features.