The combination of thio-tepa and 5 fluorouracil as a palliative therapy for breast cancer
Chauvergne, J.; Hoerni, B.; Hoerni-Simon, G.; Durand, M.
Revue Francaise de Gynecologie et d'Obstetrique 68(3): 159-165
1973
ISSN/ISBN: 0035-290X PMID: 17472211 Document Number: 66095
Over a six-year period, a total of 177 patients with far-advanced breast carcinoma have been submitted by the authors to 200 chemotherapeutical cycles combining Thio-TEPA and 5 fluorouracile according to a well-defined scheme. The efficiency was but minimally enhanced, as compared with separate use of these two drugs. According to the authors, however, the principle of multiple chemotherapy should not be questioned. In fact, the problem to be considered is connected with the indications of hormone therapy and chemotherapy, respectively.