COX-2 as an early diagnostic marker of virus-associated human malignant neoplasms
Diduk, S.V.; Smirnova, K.V.; Gurtsevich, V.É
Voprosy Virusologii 57(2): 4-8
2012
ISSN/ISBN: 0507-4088 PMID: 22834139 Document Number: 660101
The review analyzes recent data and current ideas on the enzyme cyclooxygenase 2 (COX-2) as a possible biomarker of virus-associated human malignant neoplasm. Possible mechanisms of COX-2 activation in the cells infected with oncogenic human viruses, such as hepatitis B virus, Epstein-Barr virus, and human papillomavirus are considered in detail.
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