Update on current care guidelines: psoriasis and psoriatic arthritis
Duodecim; Laaketieteellinen Aikakauskirja 128(15): 1620-1621
2012
ISSN/ISBN: 0012-7183 PMID: 22970613 Document Number: 660037
Psoriasis is a chronic, immune-mediated, inflammatory disorder of the skin and joints. Moderate-to-severe cases are associated with an independent risk of comorbidity (cardiovascular diseases and diabetes) even after adjusting for risk factors, known to be more prevalent in psoriatics compared to normal population. The underlying systemic inflammation, analogous to that observed in rheumatoid arthritis, calls for a long-term effective treatment. Screening and treatment of cardiovascular risk factors is highly recommended. The biologic drug arsenal has new additions. Long term treatment data from clinical study extensions and independent registries are reviewed.