Vitamin D and bisphosphonate-related osteonecrosis of the jaw (BRONJ)
Hokugo, A.
Clinical Calcium 22(1): 83-90
2012
ISSN/ISBN: 0917-5857 PMID: 22201103 Document Number: 659406
Bisphosphonate have been widely used for the treatment of osteoporosis and malignant hypercalcemia or bone metastasis of solid cancers. Recently bisphosphonate-related osteonecrosis of the jaw (BRONJ) has been reported. However the pathogenesis of BRONJ has been unclear. This article reviews the various hypotheses of the pathogenesis of BRONJ including our hypothesis for its pathogenesis.
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