Early administrations of statins after acute coronary syndrome
Linde, J.J.; Jensen, G.B.
Ugeskrift for Laeger 174(26): 1801-1803
2012
ISSN/ISBN: 1603-6824 PMID: 22735112 Document Number: 658685
In this Cochrane review the potential benefits and harms of early administrations of statins after acute coronary syndrome (ACS) were evaluated in 18 randomized trials including 14,303 patients. No statistically significant effect was found on the primary combined outcome of death, myocardial infarction and stroke, but at four-month follow-up the incidence of unstable angina pectoris was significantly reduced. Despite the lack of evidence for an additional effect of early statin administrations on hard clinical end points, we find good reasons to maintain statins in the early treatment of ACS.