Role of positron emission tomography in diagnosis and monitoring of sarcoidosis
Omernik, A.
Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego 33(194): 107-111
2012
ISSN/ISBN: 1426-9686 PMID: 23009009 Document Number: 658674
Positron emission tomography is a three-dimensional nuclear imaging technique. It is often use in diagnosis of neoplasms, disease of cardiovascular and central nerve system. There are some researches which show role of this method in diagnosis and monitoring some of pulmonary disease. This paper sums up current reports about role of positron emission tomography in diagnosis and monitoring of: occupancy of organs and treatment in sarcoidosis. It shows limited capability to differentiating sarcoidosis from chest malignancy at use 18-fluorodeoxyglucose as radiolabel and result of promising research which show usefulness 18-metyltyrosine in this range. We summarise papers which present benefits of PET in determination of advancing disease especially in multi-systemic and atypical cases. Advantage of PET over present use radiological patechnique in defining of sarcoidosis activity allows using it in monitoring of treatment with standard therapy and help in determination of usefulness of new drugs. Future large randomised studies could help in using this still expensive method in wide range of patient to diagnose and monitoring of sarcoidosis and other nowadays unused recommendation.