Network-based local and global consistency of cardiovascular genes

Zuo, X.; Lu, P.; Liu, X.; Chen, J.; Gao, Y.; Yang, Y.; Yang, H.; Zuo, X; Lu, P; Liu, X; Chen, J; Gao, Y; Yang, Y; Yang, H

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Network-based local and global consistency of cardiovascular genes

Zuo, X.; Lu, P.; Liu, X.; Chen, J.; Gao, Y.; Yang, Y.; Yang, H.

Zhongguo Zhong Yao Za Zhi 37(2): 130-133

2012

ISSN/ISBN: 1001-5302

PMID: 22737837

Document Number: 657470

Drug targets discovery is one of the most important elements in new drug development, and a variety of methods have been developed recently from this point of view. This paper proposed a network-based local and global consistency for cardiovascular genes identification. Results were evaluated through the widely used database HPRD and DrugBank. Results showed that our algorithm can give reasonable candidate targets set. The method in this paper could be an impressive solution for targets searching.