The role of kidney in pathogenesis of arterial hypertension
Wojtusik, S.; Sułowicz, Władysław.
Przeglad Lekarski 69(9): 680-686
2012
ISSN/ISBN: 0033-2240 PMID: 23401989 Document Number: 657358
Blood pressure control is regulated by complicated physiological mechanisms, which are dependent upon cardio-vascular, neurological, endocrine systems and the kidneys. The kidneys plays an important role in the regulation of blood pressure based on sodium and water balance, renin-an. giotensin-aldosterone axis, sympathetic activity as well as other regulatory substances like: natriuretic peptides (ANP, BNP) endothelin, dopamine, prostaglandins and nitric oxide (NO). In chronic kidney disease (CKD) patients hypertension is extremely common and is aggravated together with the lowering of renal clearance (GFR). The kidneys may be a cause and a culprit of hypertension.