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Morphological changes in autoimmune dacryoadenitis associated with thyroid eye disease

Safonova, T.N.; Likhvantseva, V.G.; Kuz'min, K.A.; Gontiurova, O.A.; Rudenko, E.I.

Vestnik Oftalmologii 128(6): 15-19

2012

ISSN/ISBN: 0042-465X
PMID: 23367755
Document Number: 656838
Increase of lacrimal gland (LG) volume was revealed in 1/3 of patients with thyroid eye disease (TED) using visualization methods. Authors show morphological data confirming development of autoimmune process in LG in TED, biopsy samples were studied within 6 hours after exitus. Specific histomorphological characteristics were analysed considering dystrophic and degenerative changes in LG tissue. Quantitative assessment of fibrosis and vascularization extent is determined using fibrosis and vascularization index.

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