Oxygenation state of brain in children upon reamberin infusion during post-anesthesia recovery
Lazarev, V.V.; Khelimskaia, I.A.; Tsypin, L.E.; Mikhel'son, V.A.; Popova, T.G.
Eksperimental'naia i Klinicheskaia Farmakologiia 75(2): 38-41
2012
ISSN/ISBN: 0869-2092 PMID: 22550859 Document Number: 656801
The effect of reamberin (1.5% solution of succinic acid and ion complex) on the oxygenation status of the brain was studied in children aged 1 - 14 years during recovery from anesthesia. It is established that reamberin in a dose of 2 ml/kg administered twice at the end of an operation increases the fraction of oxidized hemoglobin and cytochrome oxidase and enhances the regional saturation of brain tissue with oxygen, which is indicative of an increase in the potential of metabolism activation in neurons.